Dynamically adaptive numerologies for ultra-reliable low-latency communications (URLLC) are discussed in which a base station may determine performance characteristics for each user equipment (UE) that it serves, in addition to detecting any fluctuations in system loading at the base station. Based on this information, the base may be select for each of the served UEs an adapted numerology that provides an optimized set of configurations that assist the communications between the base station and each UE to meet the strict parameters for URLLC. Once selected, the base station signals the selected adapted numerology to the UEs either through broadcast or UE-specific communications.