US Patent 10423757 System and method for probabilistic ablation planning

A system and method for ablation planning includes defining (502) shapes and sizes for one or more ablation volumes based on probability of treatment, and determining (510) a target volume to be treated. A procedure plan is provided (516) by determining a number and location of planned ablations within the target volume using the one or more ablation volumes. A joint probability distribution (520) is determined for at least two planned ablations in the target volume. A final configuration is visualized (530) to determine if plan objectives are met based on a probability of treatment for the target volume.