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US Patent 10428109 Process for the preparation of 1,5-benzothiazepine compounds

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Patent abstract

The present invention relates to a process for the preparation of certain 1,5-benzothiazepine compounds, and in particular to a process for the preparation of elobixibat. The process can be carried out under mild and safe conditions and may be used to prepare elobixibat on an industrial scale. The invention also relates to a process for the preparation of a crystalline monohydrate of elobixibat.

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Patent Citations Received
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US Patent 11801226 Pharmaceutical formulation of odevixibat
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Patent Citations Received
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US Patent 11802115 Pharmaceutical formulation of odevixibat
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Patent Citations Received
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US Patent 11773071 Benzothiazepine compounds and their use as bile acid modulators
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Patent Inventor Names
Akinori Tatara0
Ganapati G. Bhat0
Johnson M. Coutinho0
Michael Lofthagen0
Mikael Dahlström0
Edits on 19 May, 2023
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=10428109
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edited on 15 Mar, 2023
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Patent Citations Received
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US Patent 11603359 Benzothiadiazepine compounds and their use as bile acid modulators
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Edits on 22 Feb, 2023
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edited on 22 Feb, 2023
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US Patent 11583539 Treating progressive familial intrahepatic cholestasis (PFIC) with IBAT inhibitors
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Patent citations received
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US Patent 11377429 Benzothia(di)azepine compounds and their use as bile acid modulators
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edited on 22 Jun, 2022
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US Patent 11365182 Crystal modifications of odevixibat
Edits on 18 Jun, 2022
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edited on 18 Jun, 2022
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=10428109
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edited on 18 May, 2022
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Patent citations received
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US Patent 11306064 Benzothia(di)azepine compounds and their use as bile acid modulators
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Patent citations received
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US Patent 11267794 Benzothia(di)azepine compounds and their use as bile acid modulators
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edited on 3 Mar, 2022
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Patent citations received
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US Patent 11261212 IBAT inhibitors for the treatment of liver diseases

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