Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 1, 2019
Patent Application Number
15990547
Date Filed
May 25, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
The application discloses methods and compositions for the inhibition of the alternative complement pathway. The methods and compositions involve the use of aptamers for inhibiting complement Factor D. The application further provides anti-Factor D aptamers for the treatment of dry age-related macular degeneration, geographic atrophy, wet age-related macular degeneration or Stargardt disease. In some cases, stem-loop aptamers are provided for the inhibition of Factor D.
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