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US Patent 10441571 Spiro-lactam NMDA receptor modulators and uses thereof

Patent 10441571 was granted and assigned to Aptinyx Inc. on October, 2019 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Aptinyx Inc.
Aptinyx Inc.
Current Assignee
Aptinyx Inc.
Aptinyx Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10441571
Patent Inventor Names
M. Amin Khan0
John A. Lowe, III0
Date of Patent
October 15, 2019
Patent Application Number
15969186
Date Filed
May 2, 2018
Patent Citations
‌
US Patent 10150769 Spiro-lactam NMDA modulators and methods of using same
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US Patent 10196401 Spiro-lactam NMDA receptor modulators and uses thereof
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US Patent 10052308 Spiro-lactam NMDA receptor modulators and uses thereof
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US Patent 10195179 Spiro-lactam NMDA receptor modulators and uses thereof
Patent Citations Received
‌
US Patent 12012413 Methods of treating painful diabetic peripheral neuropathy
0
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US Patent 11578072 Spiro-lactam NMDA receptor modulators and uses thereof
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US Patent 11299495 Spiro-lactam NMDA receptor modulators and uses thereof
0
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US Patent 11376250 Spiro-lactam NMDA receptor modulators and uses thereof
‌
US Patent 11427585 Spiro-lactam NMDA modulators and methods of using same
0
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US Patent 11512051 Spiro-lactam NMDA receptor modulators and uses thereof
‌
US Patent 11530223 Spiro-lactam NMDA receptor modulators and uses thereof
0
Patent Primary Examiner
‌
Craig D Ricci
Patent abstract

Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.

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