Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Micha A. Häuptle0
Michael L. Wetter0
Michael T. Kowarik0
Stefan J. Kemmler0
Veronica Gambillara0
Manuela Mally0
Date of Patent
October 15, 2019
0Patent Application Number
156437880
Date Filed
July 7, 2017
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein is a novel E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells containing enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates contain O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, including O25B and/or bioconjugates containing O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further include one or more additional bioconjugates.
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