Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Atsushi Muto0
Chifumi Imai0
Kazutaka Yoshihashi0
Takehisa Kitazawa0
Tetsuhiro Soeda0
Tetsuo Kojima0
Tomoyuki Igawa0
Tsukasa Suzuki0
...
Date of Patent
October 22, 2019
0Patent Application Number
151329960
Date Filed
April 19, 2016
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.
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