A method for operating a quantum processing device is provided including at least two quantum circuits coupled to a tunable coupler, wherein the quantum circuits are subject to cross-talk, the method including: applying a primary signal to the quantum circuits so as to drive one or more energy transitions between states spanned by the quantum circuits; and applying a compensation signal to the tunable coupler, the compensation signal designed so as to shift at least one state spanned by the quantum circuits, in energy, to compensate for cross-talk between the quantum circuits. Related quantum processing devices and chips are also provided.