Patent 10457714 was granted and assigned to Zealand Pharma A/S on October, 2019 by the United States Patent and Trademark Office.
The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.