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US Patent 10471426 Microfluidic device and array disk

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
104714260
Patent Inventor Names
Weimin Gao0
Rhett Martineau0
Shih-Hui Chao0
Shufang Ci0
Deirdre Meldrum0
Jeff Houkal0
Date of Patent
November 12, 2019
0
Patent Application Number
160354640
Date Filed
July 13, 2018
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Patent Citations
‌
US Patent 10022718 Microfluidic device and array disk
Patent Citations Received
‌
US Patent 10940476 Device for high-throughput multi-parameter functional profiling of the same cells in multicellular settings and in isolation
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US Patent 11345954 Methods for digital readout quantification of nucleic acids
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US Patent 11315292 Live-cell computed tomography
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US Patent 11332782 Method for detecting nucleotide polymorphisms
Patent Primary Examiner
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Brian J. Sines
0
Patent abstract

The invention relates to microfluidic devices and array disks for “one-pot” isolated chemical reactions. The array disks comprise a plurality of sectors in which each sector comprises one microfluidic device. The microfluidic devices comprise a fluid delivery channel and an array of wells wherein the fluid delivery channel delivery fluid into the wells in a serpentine arrangement. In some embodiments, the fluid delivery channel is directly above the array of wells. In other embodiments, the fluid delivery channel is offset from the array of wells so that side channels branching from the fluid delivery channel delivers fluid into the wells. The well of the microfluidic device comprises a gas-permeable membrane that forms the floor, well, or at least a portion of the floor or wall of the well. In preferred embodiments, the well is cylindrical.

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