US Patent 10494437 Heterodimer protein composition
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Patent abstract
According to the present invention, a heterodimer protein composition that is composed of a first polypeptide comprising an immunoglobulin heavy chain constant region and a second polypeptide comprising CL-Fc prepared by fusion of an immunoglobulin light chain constant region (CL) and Fc region, and also has a deletion or substitution of Cys residues involved in disulfide bonds between CL and CH1, a purification method of the protein composition thereof, a preparation method of the protein composition thereof, a DNA and a vector encoding the protein composition thereof are provided.
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Patent Inventor Names
Mami Tsuchiya0
Rinpei Niwa0
Takuya Murakami0
Yuta Tezuka0
Edits on 23 Sep, 2022
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Patent Applicant
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Patent Number
104944370
Date of Patent
December 3, 2019
0Patent Application Number
156245810
Date Filed
June 15, 2017
0Patent Primary Examiner
Edits on 30 Jan, 2022
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US Patent 10494437 Heterodimer protein composition
Infobox
Is a
Patent applicant
Patent jurisdiction
Patent number
10494437
Date of patent
December 3, 2019
Patent application number
15624581
Date Filed
June 15, 2017
Patent primary examiner
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