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US Patent 10501442 Quinoline derivative

Patent 10501442 was granted and assigned to Ono Pharmaceuticals on December, 2019 by the United States Patent and Trademark Office.

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Current Assignee
Ono Pharmaceuticals
Ono Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
105014420
Patent Inventor Names
Jun Takeuchi0
Takayuki Inukai0
Tomoko Yasuhiro0
Date of Patent
December 10, 2019
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Patent Application Number
162372750
Date Filed
December 31, 2018
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Patent Citations Received
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US Patent 11826363 Therapeutic agent for solid cancers, which comprises Axl inhibitor as active ingredient
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Patent Primary Examiner
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Brian J Davis
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Patent abstract

A compound represented by general formula (I) has a strong Axl inhibitory activity by introducing a distinctive bicyclic structure in which a saturated carbon ring is fused to a pyridone ring, and can be a therapeutic agent for Axl-related diseases, for example, cancer such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases

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