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US Patent 10525143 Conjugate of polyethylene glycol and anesthetic, and preparation method thereof

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10525143
Date of Patent
January 7, 2020
Patent Application Number
15848987
Date Filed
December 20, 2017
Patent Citations Received
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US Patent 11377422 Charged ion channel blockers and methods for use
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US Patent 11696912 Charged ion channel blockers and methods for use
0
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US Patent 11332446 Charged ion channel blockers and methods for use
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US Patent 11512058 Charged ion channel blockers and methods for use
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US Patent 10786485 Charged ion channel blockers and methods for use
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US Patent 10828287 Charged ion channel blockers and methods for use
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US Patent 10842798 Charged ion channel blockers and methods for use
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US Patent 10927096 Ester substituted ion channel blockers and methods for use
...
Patent Primary Examiner
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Johann R. Richter
Patent abstract

A conjugate represented by general formula (I), wherein R0 is a C1-6 alkyl, B is an anesthetic, and A is a linking group, and a quaternary ammonium salt is formed at the linking position between B and R0. The conjugate has a prolonged analgesic effect, and can be used in postoperative analgesia or treatment for chronic pain.

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