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US Patent 10568878 Combination therapy

Patent 10568878 was granted and assigned to Aerie Pharmaceuticals on February, 2020 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Current Assignee

Aerie Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Mitchell A. deLong0

Casey Kopczynski0

Cheng-Wen Lin0

Jill Marie Sturdivant0

Date of Patent

February 25, 2020

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Patent Application Number

159013610

Date Filed

February 21, 2018

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Patent Citations

US Patent 10112920 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

US Patent 10174017 Dual mechanism inhibitors for the treatment of disease

Patent Citations Received

US Patent 12018012 Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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US Patent 11028081 Dual mechanism inhibitors for the treatment of disease

US Patent 11590123 Ophthalmic compositions

US Patent 11618748 Dual mechanism inhibitors for the treatment of disease

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US Patent 11707460 Ophthalmic compositions

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US Patent 11891376 Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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Patent Primary Examiner

James D. Anderson

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Patent abstract

Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound and a prostaglandin or prostaglandin analog. Compounds described herein include those in which an isoquinoline compound is covalently linked to a prostaglandin or a prostaglandin analog, and those in which an isoquinoline compound and a prostaglandin free acid together form a salt.

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