The present disclosure is directed to autonomous vehicle platforms and autonomous vehicles including such platforms. For example, an autonomous vehicle can include a bisymmetrical platform including a first portion, a second portion, a third portion and a fourth portion that collectively provide a supporting structure for the autonomous vehicle and that respectively comprise a wheel mounting frame configured for location of a wheel assembly. A body including front and rear sides and first and second lateral sides can be positioned on top of the bisymmetrical platform configured to receive passengers for transport. The autonomous vehicle can also include a plurality of wheel assemblies configured for secure positioning relative to each wheel mounting frame within the bisymmetrical platform and a powertrain configured to power the plurality of wheel assemblies for operation of the autonomous vehicle to travel in either a forward direction or a rear direction.