US Patent 10573003 Systems and methods for computational pathology using points-of-interest

Systems, methods and devices for determination of disease class scores for patient tissue are disclosed. The disease class scores may be based on the probability or probability-like metric for a disease condition or outcome. The system includes an imaging apparatus and a computing system with instructions executable by a processor. The computer system may locate one or more points-of-interest on the pre-processed images of the patient tissue using a point-of-interest detector and generate one or more disease spatial maps including one or more probability or probability-like metric of disease classifications on the detected points-of-interest. The information in the disease spatial maps is aggregated to produce disease class scores.