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US Patent 10577390 Compositions and methods for treating CNS disorders

Patent 10577390 was granted and assigned to SAGE Therapeutics on March, 2020 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
SAGE Therapeutics
SAGE Therapeutics
Current Assignee
SAGE Therapeutics
SAGE Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10577390
Patent Inventor Names
Boyd L. Harrison0
Gabriel Martinez Botella0
Francesco G. Salituro0
Albert J. Robichaud0
Date of Patent
March 3, 2020
Patent Application Number
15519480
Date Filed
October 16, 2015
Patent Citations
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US Patent 10246482 Neuroactive steroids, compositions, and uses thereof
Patent Citations Received
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US Patent 12083131 Neuroactive steroids, compositions, and uses thereof
0
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US Patent 11634453 Neuroactive steroids substituted in position 10 with a cyclic group for use in the treatment of CNS disorders
0
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US Patent 11945836 Compositions and methods for treating CNS disorders
0
0
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US Patent 12060386 Compositions and methods for treating CNS disorders
0
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US Patent 12065463 Compositions and methods for treating CNS disorders
0
Patent Primary Examiner
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Angela C Brown-Pettigrew
Patent abstract

Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein (II), A, R1, R2, R3a, R4a, R4b, R5, R7a, and R7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

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