Provided is a stroke diagnosis apparatus based on AI that includes: an image obtainer obtaining a non-contrast CT image related to the brain of at least one patient; a preprocessor pre-processing the non-contrast CT image and determining whether the at least one patient is in a non-hemorrhage state or a hemorrhage state on the basis of the pre-processed image; an image processor normalizing the pre-processed image and dividing and extracting an ROI (Region of Interest) using a preset standard mask template; and a determiner determining whether there is a problem with a cerebral large vessel of the at least one patient using the divided and extracted ROI.