Patent attributes
Fenestrated tissue grafts and acellular dermal matrices (ADMs) for use, for example, in breast reconstruction, are disclosed herein. In various embodiments, the improved tissue grafts are used in two-stage tissue expander breast reconstruction. Disclosed embodiments include altered ADMs and other tissue grafts, which comprise strategically placed fenestrations, and methods of making the same. The addition of specific patterns of fenestrations in the graft improve the breast reconstructive experience by increasing intra-operative fill volume and decreasing time to full expansion; such alterations to the graft may also increase cosmetic outcomes and patient comfort. In some embodiments, particular lengths, shapes, and measurements of overlap are used in the fenestration pattern.