Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Joseph Wiencek0
Michael Kalafatis0
Date of Patent
January 26, 2021
Patent Application Number
15766901
Date Filed
October 7, 2016
Patent Citations Received
Patent Primary Examiner
Patent abstract
During the process of coagulation, prothrombin is activated to α-thrombin by prothrombinase. Key residues in the structure of prothrombin allow for modulation of the activation of prothrombin. In certain embodiments, a recombinant prothrombin with at least one point mutation or deletion is provided.
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