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US Patent 10906929 Phosphoramidate nucleoside derivatives as anticancer agents

Patent 10906929 was granted and assigned to NuCana on February, 2021 by the United States Patent and Trademark Office.

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Patent abstract

This invention relates to derivatives of cladribine of Formula (I). The compounds are phosphoramidate derivatives in which the phosphoramidate moiety is situated on the 3′-hydroxyl group of cladribine. The invention also relates to pharmaceutical formulations of the cladribine derivatives and their use in methods of treatment. The compounds are useful in the treatment of cancer.

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Patent Inventor Names
Christopher McGuigan0
Hugh Griffith0
Magdalena Slusarczyk0
Michaela Serpi0
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=109069290
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Patent Citations Received
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US Patent 11560400 Salts of diphosphate phosphoramidate of nucleosides as anticancer compounds
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=10906929
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 US Patent 10906929 Phosphoramidate nucleoside derivatives as anticancer agents

Infobox
Is a
Patent
Patent
Patent applicant
NuCana
NuCana
Current assignee
NuCana
NuCana
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10906929
Date of patent
February 2, 2021
Patent application number
16305153
Date Filed
May 31, 2017
Patent citations
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US Patent 10022390 Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer
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US Patent 10117888 Formulation comprising a gemcitabine-prodrug
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US Patent 10786523 Formulation comprising a gemcitabine-prodrug
Patent primary examiner
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Lawrence E Crane

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