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US Patent 10912792 Compounds and methods for modulating angiotensinogen expression

Patent 10912792 was granted and assigned to Ionis Pharmaceuticals on February, 2021 by the United States Patent and Trademark Office.

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Patent abstract

Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating AGT and modulating a RAAS pathway related disease, disorder and/or condition in an individual in need thereof. A RAAS pathway related disease, disorder and/or condition in an individual such as hypertension can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to AGT.

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