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US Patent 10920227 Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

Patent 10920227 was granted and assigned to Voyager Therapeutics on February, 2021 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Voyager Therapeutics

Current Assignee

Voyager Therapeutics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

February 16, 2021

Patent Application Number

16774493

Date Filed

January 28, 2020

Patent Citations

US Patent 10047377 Methods for modulating KLHL1 levels, methods for modulating current activity in T-type calcium channels, molecules therefor, and methods for identifying molecules therefor

US Patent 10041090 Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby

Patent Citations Received

US Patent 12123002 Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

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US Patent 11931375 Treatment of amyotrophic lateral sclerosis (ALS)

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US Patent 12116589 Treatment of amyotrophic lateral sclerosis (ALS)

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US Patent 11542506 Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

US Patent 11603542 Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

US Patent 11649459 Superoxide dismutase 1 (SOD1) iRNA compositions and methods of use thereof for treating or preventing superoxide dismutase 1-(SOD1-) associated neurodegenerative diseases

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US Patent 11434502 Treatment of amyotrophic lateral sclerosis (ALS)

US Patent 11912997 RNAi agents for inhibiting expression of Superoxide Dismutase 1 (SOD1), compositions thereof, and methods of use

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Patent Primary Examiner

Ekaterina Poliakova-Georgantas

Patent abstract

The present invention relates to small interfering RNA (siRNA) molecules against the SOD1 gene, adeno-associated viral (AAV) vectors encoding siRNA molecules and methods for treating amyotrophic lateral sclerosis (ALS) using the siRNA molecules and AAV vectors.

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