Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Joel H. Martin0
Douglas Macdonald0
Mark W. Sleeman0
Tammy T. Huang0
Date of Patent
March 9, 2021
0Patent Application Number
159967730
Date Filed
June 4, 2018
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
An human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human proprotein convertase subtilisin/kexin type 9 (hPCSK9) characterized by the ability to reduce serum LDL cholesterol by 40-80% over a 24, 60 or 90 day period relative to predose levels, with little or no reduction in serum HDL cholesterol and/or with little or no measurable effect on liver function, as determined by ALT and AST measurements.
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