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US Patent 10941395 Method for gene editing

Patent 10941395 was granted and assigned to Massachusetts Institute of Technology on March, 2021 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Massachusetts Institute of Technology

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Current Assignee

Massachusetts Institute of Technology

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Tyler E. Jacks0

Daniel G. Anderson0

Hao Yin0

Joseph R. Dorkin0

Wen Xue0

Date of Patent

March 9, 2021

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Patent Application Number

160292730

Date Filed

July 6, 2018

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Patent Citations

US Patent 10047355 Delivery systems and kits for gene editing

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Patent Citations Received

US Patent 11446394 Lipid nanoparticle formulations comprising lipidated cationic peptide compounds for nucleic acid delivery

US Patent 12123032 CRISPR enzyme mutations reducing off-target effects

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US Patent 11701434 Tertiary amino lipidated cationic peptides for nucleic acid delivery

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Patent Primary Examiner

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Patent abstract

The present disclosure relates to compositions and methods for modifying a gene sequence, and for systems for delivering such compositions. For example, the disclosure relates to modifying a gene sequence using a CRISPR-Cas9 or other nucleic acid editing system, and methods and delivery systems for achieving such gene modification, such as viral or non-viral delivery systems.

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