Patent 10954554 was granted and assigned to Massachusetts Institute of Technology on March, 2021 by the United States Patent and Trademark Office.
The invention relates to a kit for preparing a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a kit for preparing a library of template polynucleotides suitable for methylation analysis.