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US Patent 10975120 Site-specific chemoenzymatic protein modifications

Patent 10975120 was granted and assigned to Novartis on April, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.

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