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US Patent 10975374 Combination vectors and methods for treating cancer

Patent 10975374 was granted and assigned to American Gene Technologies on April, 2021 by the United States Patent and Trademark Office.

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Patent abstract

A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.

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