US Patent 10995336 Serpina1 iRNA compositions and methods of use thereof
Patent 10995336 was granted and assigned to Alnylam Pharmaceuticals on May, 2021 by the United States Patent and Trademark Office.
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Patent abstract
The invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.
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Patent Inventor Names
Alexander V. Kel'in0
Alfica Sehgal0
Christopher Brown0
Donald Foster0
Jayaprakash K. Nair0
Kallanthottathil G. Rajeev0
Kevin Fitzgerald0
Klaus Charisse0
Maja Janas0
Mark K. Schlegel0
Martin A. Maier0
Muthiah Manoharan0
Muthusamy Jayaraman0
Shigeo Matsuda0
Stuart Milstein0
Vasant R. Jadhav0
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US Patent 10995336 Serpina1 iRNA compositions and methods of use thereof
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Patent applicant
Current assignee
Patent jurisdiction
Patent number
10995336
Date of patent
May 4, 2021
Patent application number
16420263
Date Filed
May 23, 2019
Patent citations
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