Devices, systems, and methods of the present disclosure are directed to dispensing wipes that are treated as the wipes move through a housing of a dispenser. Such in situ treatment of the wipes may facilitate, for example, achieving control over one or more of the concentration, composition, or distribution of one or more chemicals carried by the wipes. Further, or instead, the one or more chemicals may be formed within the housing (e.g., just prior to treating the wipes), which may be useful for treating the wipes with chemicals that have limited stability and/or for reducing chemical handling requirements along a supply chain.