Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 25, 2021
Patent Application Number
16060406
Date Filed
December 9, 2016
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.
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