Is a
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Patent Applicant
0
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Melissa Jane Birch0
Stephen Mark McAllister0
Ian Leonard Smales0
Klimentina Dimitrova Pencheva0
Martin Gregory Rowland0
Date of Patent
June 1, 2021
0Patent Application Number
165357470
Date Filed
August 8, 2019
0Patent Citations Received
Patent Primary Examiner
Patent abstract
This invention relates to acrystalline form of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h] [2,5,11]benzoxadiazacyclo-tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.
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