Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brian R. Sloat0
Michael A. Sandoval0
Steven J. Prestrelski0
Date of Patent
June 1, 2021
0Patent Application Number
159948320
Date Filed
May 31, 2018
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
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