Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Pradip Nair0
Usha Bughani0
Abhijit Barve0
Bala S. Manian0
Jose Enrique Montero Casimiro0
Ramakrishnan Melarkode0
Date of Patent
June 8, 2021
0Patent Application Number
162154960
Date Filed
December 10, 2018
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure relates to methods for treatment and prevention of disease conditions mediated by T-helper 17 (Th17) and/or T-helper 1 (Th1) T lymphocytes (T cells). In particular, the present disclosure relates to use of anti-CD6 antibody for treatment of disease conditions mediated by auto-reactive Th17 and Th1 T lymphocytes. The methods of the present disclosure further have utility in methods for modulating an immune response by suppressing production of the cytokine IL-23R, thereby decreasing inflammation mediated by Th17 cells.
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