Patent 11041153 was granted and assigned to Bio-Path Holdings on June, 2021 by the United States Patent and Trademark Office.
Provided herein are improved delivery systems for oligonucleotides, said delivery system comprising a liposome that comprises neutral phospholipids and a P-ethoxy oligonucleotide, which targets a STAT3-encoding polynucleotide. Methods of treating patients with said delivery systems are also provided.