A color-coded roller clamp apparatus for easily clamping an IV tube includes a clamp housing having a clamp inside. A top aperture and a roller slot extend through to the clamp inside. The clamp housing is configured to receive an IV tube passing through the top aperture and out a bottom. A roller is coupled to the clamp housing and comprises a wheel partially extending through the roller slot. A first hemisphere and a second are a first color and a second color, respectively. An axle is coupled to the wheel within the clamp. The roller is rollingly moveable between a disengaged position alternative engaged. The wheel in the disengaged position exposes the first hemisphere through the roller slot and the wheel in the engaged position exposes the second hemisphere through the roller slot and is configured to clamp the IV tube against the back side to prevent flow.