The present invention provides floor mats possessing antipathogenic, cohesive, viscoelastomeric and adhesive attributes for removing foot and/or sole borne contaminants. A thermoset reaction product derived from a reaction media of a carefully balanced ratio of isocyanate prepolymer, polyether diols and triols, and organic plasticizers effectively provides a floor mat overlay for adhesively retaining and preventing the spreading of foot or sole borne pathogens and other contaminants.