Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
James Bradner0
Dennis Buckley0
Georg Winter0
Date of Patent
July 13, 2021
Patent Application Number
16838656
Date Filed
April 2, 2020
Patent Citations
Patent Primary Examiner
Patent abstract
The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of cancer. The present application also provides compounds of Formula X0 and X0′:
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