Patent 11065306 was granted and assigned to Alexion Pharmaceuticals on July, 2021 by the United States Patent and Trademark Office.
The disclosure features methods for treating hypophosphatasia (HPP) in a patient (e.g., a child having HPP) exhibiting physical impairments, disability in activities of daily living (ADL), pain, and/or delayed motor development by administering a soluble alkaline phosphatase (sALP) to the patient.