Patent 11067584 was granted and assigned to Genzyme on July, 2021 by the United States Patent and Trademark Office.
Provided are methods for quantitating an amount of a polypeptide that comprises a portion of an antibody present in a sample (e.g., a plasma or serum sample) wherein the antibody comprises a constant region (e.g., a heavy chain or light chain constant region) that comprises an engineered mutation.