Patent 11071782 was granted and assigned to Coherus BioSciences on July, 2021 by the United States Patent and Trademark Office.
The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.