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US Patent 11072794 Compositions and their uses directed to huntingtin

Patent 11072794 was granted and assigned to Ionis Pharmaceuticals on July, 2021 by the United States Patent and Trademark Office.

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Patent abstract

Disclosed herein are compounds, compositions and methods for modulating the expression of huntingtin in a cell, tissue or animal. Further provided are methods of slowing or preventing Huntington's Disease (HD) progression using an antisense compound targeted to huntingtin. Additionally provided are methods of delaying or preventing the onset of Huntington's Disease (HD) in an individual susceptible to Huntington's Disease (HD). Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.

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