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US Patent 11118164 Pepmixes to generate multiviral CTLs with broad specificity

Patent 11118164 was granted and assigned to Baylor College of Medicine on September, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.

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