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US Patent 11124497 Inhibitors of cysteine proteases and methods of use thereof

Patent 11124497 was granted and assigned to Pardes Biosciences, Inc on September, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The disclosure provides compounds with warheads and their use in treating medical diseases or disorders, such as viral infections. Pharmaceutical compositions and methods of making various compounds with warheads are provided. The compounds are contemplated to inhibit proteases, such as the 3C, CL- or 3CL-like protease. Exemplary compounds provided include Formula II-I, where R3, RB are provided herein:

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