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US Patent 11124514 Compositions and methods

Patent 11124514 was granted and assigned to Intra-Cellular Therapies on September, 2021 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Intra-Cellular Therapies

Current Assignee

Intra-Cellular Therapies

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

September 21, 2021

Patent Application Number

20190927

Date Filed

September 27, 2019

Patent Citations Received

US Patent 12128043 Pharmaceutical capsules comprising lumateperone mono-tosylate

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US Patent 12090155 Methods

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US Patent 12122792 Pharmaceutical compositions comprising 4-((6bR,10aS)-3-methyl2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders

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US Patent 11690842 Pharmaceutical capsule compositions comprising lumateperone mono-tosylate

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US Patent 11753419 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders

US Patent 11773095 Organic compounds

US Patent 11440911 Salts and crystals

US Patent 11958852 Compounds and methods

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Patent abstract

The present invention relates to use of particular substituted heterocycle fused gamma-carbolines as described herein, in free, pharmaceutically acceptable salt or prodrug form, and pharmaceutical composition comprising the same optionally in combination with one or more agents, for the prophylaxis or treatment of one or more disorders associated with dementia, particularly behavioral or mood disturbances (e.g., agitation/aggression), psychosis, depression and sleep disturbances among others in patients suffering from dementia.

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