US Patent 11155818 MicroRNA hsa-miR-665 in cardiac hypertrophy

Patent 11155818 was granted and assigned to King's College London on October, 2021 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

King's College London

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

111558180

Patent Inventor Names

Miguel Luis Cunha Mano0

Matteo Dal Ferro0

Mauro Giacca0

Ana Sofia Bregieiro Eulalio0

Luca Braga0

Date of Patent

October 26, 2021

Patent Application Number

201803130

Date Filed

March 13, 2018

Patent abstract

The present invention refers to human microRNA hsa-miR-665 for the treatment or prevention of heart diseases associated with cardiac hypertrophy and consequent pathological remodeling of the heart, in particular for preventing and/or treating heart failure (HF). Vectors and pharmaceutical compositions comprising said miRNA for the disclosed uses are also within the scope of the present invention.

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