Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
November 16, 2021
Patent Application Number
16251970
Date Filed
January 18, 2019
Patent Citations Received
Patent Primary Examiner
Patent abstract
Described herein are CRISPR/Cas9 constructs designed for the C-terminal truncation of human amyloid precursor protein (APP) as well as methods of making and using such a construct. A Cas9 nuclease/gRNA ribonucleoprotein directs cleavage of an APP gene to provide a C-terminal truncated APP having a length of 659, 670, 676, or 686 amino acids, relative to the human or mouse APP sequence.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
