A fluid detection panel is disclosed. The fluid detection panel includes a microfluidic substrate, an optical unit and a sensor. The microfluidic substrate includes a sample detection area and a comparison detection area which are arranged in parallel, and the sample detection area is configured to allow a liquid sample to arrive at the sample detection area; the optical unit is configured to provide first light and to allow the first light to be incident on both of the sample detection area and the comparison detection area; and the sensor collects the first light which passes through the sample detection area and the first light which passes through the comparison detection area.