The present disclosure relates to the field of commercial scale production and processing of biosynthetic cannabinoids produced by growing genetically modified microalgae in a photo-bioreactor to a produce biosynthetic cannabinoids, separating a liquid nutrient medium from the genetically modified microalgae, and extracting the biosynthetic cannabinoids to produce an extracted biosynthetic cannabinoid, then distilling the extracted biosynthetic cannabinoid to produce the biosynthetic cannabinoid distillate. Biosynthetic cannabinoid distillates may be used foodstuffs, beverages, nanoemulsions, spray-dried water-soluble powders, cosmetics, or topicals.