Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 30, 2021
Patent Application Number
17206685
Date Filed
March 19, 2021
Patent Primary Examiner
Patent abstract
The disclosure provides CD40-binding molecules comprising engineered human IgG domains, for example, human IgG1, IgG2, and IgG4 variants having mutations in the hinge domain, which exhibit altered binding activity to one or more Fcγ receptors. Also described herein are methods for selectively activating or inhibiting immune responses in a subject using the CD40-binding molecules.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
